Table 3. Overall incidence of major outcomes after the index SVT.
Events, n (%) | Incidence rate per 100 pt-years (95% CI) | |
---|---|---|
Thrombotic events | 31 (17.1) | 4.2 (2.9–5.9) |
Venous thrombosis | 19 (10.5) | 2.5 (1.6–4.0) |
Recurrent SVT | 1.9 (1.1–3.1) | |
Hepatic vein thrombosis | 3 (1.7) | |
Portal vein thrombosis | 4 (2.2) | |
Mesenteric vein thrombosis | 6 (3.1) | |
Splenic vein thrombosis | 1 (0.6) | |
Venous thrombosis at other sites | 0.6 (0.2–1.5) | |
DVT | 2 (1.1) | |
PE | 2 (1.1) | |
Cerebral vein thrombosis | 1 (0.6) | |
Arterial thrombosis | 10 (5.5) | 1.3 (0.7–2.4) |
Unstable angina | 1 (0.6) | |
Myocardial infarction | 2 (1.1) | |
Ischaemic stroke | 3 (1.7) | |
Peripheral artery thrombosis | 3 (1.7) | |
Retinal artery thrombosis | 1 (0.6) | |
Not specified | 2 (1.1) | |
Major bleeding | 16 (8.8) | 2.1 (1.3–3.5) |
CNS | 4 (2.2) | |
Gastrointestinal | 6 (3.1) | |
Muscle hematoma | 2 (1.1) | |
Unspecified | 4 (2.2) | |
Hematologic evolutions | 15 (8.3) | 2.0 (1.2–3.3) |
MF | 11 (6.1) | |
AML | 4 (2.2) | |
Solid cancer | 4 (2.2) | 0.5 (0.2–1.3) |
Brain glioblastoma | 1 (0.5) | |
Breast cancer | 1 (0.5) | |
Nose skin cancer | 1 (0.5 | |
Pancreas cancer | 1 (0.5) | |
Deaths | 14 (7.7) | 1.9 (1.1–3.1) |
ICH | 1 (0.6) | |
Infection | 1 (0.6) | |
MF | 1 (0.6) | |
AML | 4 (2.2) | |
Solid tumour | 2 (1.1) | |
Other | 2 (1.1) | |
Unknown | 3 (1.7) |
Abbreviations: AML, acute myeloid leukemia; CI, confidence interval; CNS, central nervous system; DVT, deep vein thrombosis; ICH, intracranial haemorrhage; MF, myelofibrosis; PE, pulmonary embolism; pt-years, patient years; SVT, splanchnic vein thrombosis