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. 2016 Nov 11;6(11):e499. doi: 10.1038/bcj.2016.105

Table 2. Risk of death according to calendar period, time from and age at CLL diagnosis.

Calendar period 1978–1984 1985–1991 1992–1998 1999–2005 2006–2013
Time since diagnosis
 <365 days 8.5 (7.8–9.3) 6.5 (5.9–7.1) 4.2 (3.7– 4.68) 3.4 (3.1–3.8) 2.6 (2.3–3.0)
 14 years 3.6 (3.3–4.0) 3.1 (2.9–3.4) 2.3 (2.2–2.6) 2.3 (2.1–2.4) 1.9 (1.7–2.1)
 510 years 3.7 (3.3–4.1) 3.0 (2.7–3.3) 2.5 (2.2–2.7) 2.3 (2.1–2.5) 1.9 (1.5–0.4)
 10–15 years 3.1 (2.6–3.7) 2.3 (2.0–2.8) 2.2 (1.9–2.5) 1.9 (1.6–2.3) NA
 >15 years 1.7 (1.3–2.1) 1.9 (1.6–2.3) 2.0 (1.6–2.5) NA NA
 Overall>365 days 3.4 (3.2–3.6) 2.8 (2.7–3.0) 2.3 (2.2–2.5) 2.3 (2.1–2.4) 1.9 (1.7–2.1)
 Index 1.4 (1.3 1.6) 1.2 (1.1–1.3) Ref. 1.0 (0.9–1.0) 0.8 (0.7–0.9)
           
Age at diagnosis
 ⩽54 7.7 (6.3–9.3) 6.4 (5.3–7.8) 7.8 (6.4–9.4) 5.9 (4.6–7.4) 2.8 (1.2–6.3)
 55–64 4.8 (4.3–5.5) 3.6 (3.2–4.1) 3.9 (3.4–4.3) 3.2 (2.8–3.8) 3.1 (2.4–4.0)
 65–74 3.0 (2.7–3.3) 2.9 (2.7–3.2) 2.3 (2.1–2.6) 2.4 (2.2–2.7) 2.3 (2.0–2.8)
 75–84 2.6 (2.3–2.9) 2.2 (2.0–2.5) 1.9 (1.7–2.0) 1.9 (1.7–2.1) 1.8 (1.5–2.0)
 ⩾85 2.4 (1.8–3.2) 1.9 (1.6–2.4) 1.7 (1.4–2.0) 1.6 (1.3–1.8) 1.3 (1.0–1.6)

Rate ratios of death for CLL patients compared with age, region of residence and gender matched background population by calendar period of diagnosis (1978–1984, 1985–1991, 1992–1998, 1999–2005 and 2006-–013), time since and age at diagnosis.

Abbreviation: NA, not applicable.