Table 2. Risk of death according to calendar period, time from and age at CLL diagnosis.
Calendar period | 1978–1984 | 1985–1991 | 1992–1998 | 1999–2005 | 2006–2013 |
---|---|---|---|---|---|
Time since diagnosis | |||||
<365 days | 8.5 (7.8–9.3) | 6.5 (5.9–7.1) | 4.2 (3.7– 4.68) | 3.4 (3.1–3.8) | 2.6 (2.3–3.0) |
1–4 years | 3.6 (3.3–4.0) | 3.1 (2.9–3.4) | 2.3 (2.2–2.6) | 2.3 (2.1–2.4) | 1.9 (1.7–2.1) |
5–10 years | 3.7 (3.3–4.1) | 3.0 (2.7–3.3) | 2.5 (2.2–2.7) | 2.3 (2.1–2.5) | 1.9 (1.5–0.4) |
10–15 years | 3.1 (2.6–3.7) | 2.3 (2.0–2.8) | 2.2 (1.9–2.5) | 1.9 (1.6–2.3) | NA |
>15 years | 1.7 (1.3–2.1) | 1.9 (1.6–2.3) | 2.0 (1.6–2.5) | NA | NA |
Overall>365 days | 3.4 (3.2–3.6) | 2.8 (2.7–3.0) | 2.3 (2.2–2.5) | 2.3 (2.1–2.4) | 1.9 (1.7–2.1) |
Index | 1.4 (1.3 –1.6) | 1.2 (1.1–1.3) | Ref. | 1.0 (0.9–1.0) | 0.8 (0.7–0.9) |
Age at diagnosis | |||||
⩽54 | 7.7 (6.3–9.3) | 6.4 (5.3–7.8) | 7.8 (6.4–9.4) | 5.9 (4.6–7.4) | 2.8 (1.2–6.3) |
55–64 | 4.8 (4.3–5.5) | 3.6 (3.2–4.1) | 3.9 (3.4–4.3) | 3.2 (2.8–3.8) | 3.1 (2.4–4.0) |
65–74 | 3.0 (2.7–3.3) | 2.9 (2.7–3.2) | 2.3 (2.1–2.6) | 2.4 (2.2–2.7) | 2.3 (2.0–2.8) |
75–84 | 2.6 (2.3–2.9) | 2.2 (2.0–2.5) | 1.9 (1.7–2.0) | 1.9 (1.7–2.1) | 1.8 (1.5–2.0) |
⩾85 | 2.4 (1.8–3.2) | 1.9 (1.6–2.4) | 1.7 (1.4–2.0) | 1.6 (1.3–1.8) | 1.3 (1.0–1.6) |
Rate ratios of death for CLL patients compared with age, region of residence and gender matched background population by calendar period of diagnosis (1978–1984, 1985–1991, 1992–1998, 1999–2005 and 2006-–013), time since and age at diagnosis.
Abbreviation: NA, not applicable.