Table 1. A comparison of chemokine-binding profiles of BPSV-CBP and ORFV-CBP shows that both viral CBPs share broad-specificity chemokine-binding properties.
| BPSV-CBP | BPSV-CBP | ORFV-CBP | ORFV-CBP | ||
|---|---|---|---|---|---|
| Chemokines | ELISA [21] | SPR | ELISA [20] | SPR [18–20] | |
| α | CXCL1 | NT | + | NT | NT |
| CXCL2 | + | ++ | + | NT | |
| CXCL4 | + | + | + | + | |
| CXCL8 | - | NT | - | NT | |
| CXCL10 | - | - | - | - | |
| CXCL12 | - | - | - | NT | |
| β | CCL2 | + | ++ | + | ++ |
| CCL3 | + | ++ | ++ | ++ | |
| CCL5 | + | +++ | ++ | +++ | |
| CCL19 | ++ | +++ | ++ | +++ | |
| CCL21 | NT | ++ | NT | + | |
| CCL22 | NT | - | NT | NT | |
| γ | XCL1 | + | + | + | + |
| δ | CX3CL1 | - | - | - | NT |
+++ <100 pM
++ 100–1000 pM
+ >1 nM