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. 2016 Dec 9;11(12):e0167964. doi: 10.1371/journal.pone.0167964

Fig 2. Mcpt4-/- mice in ovariectomy- and vitamin A-induced osteoporosis models.

Fig 2

A) Body weight 6 weeks after sham (n = 5) or ovariectomy (OVX) in wt (sham, OVX) (n = 7) and Mcpt4-/- (OVX) (n = 4). B) Femur trabecular density and cortical thickness in animals as described in (A). C) Body weight after 1 week of hypervitaminosis A at the age of 7 months. Number of animals in each group are wt controls (Cont, wt; n = 6), Mcpt4-/- controls (Cont, Mcpt4-/-; n = 5), controls vitamin A (Vitamin A, wt; n = 5) and vitamin A Mcpt4-/- (Vitamin A, Mcpt4-/-; n = 5). D) Femur diaphyseal total cross sectional area (Total area) after 1 week of hypervitaminosis A. Results are given as means ± SD. p < 0.05 *, p < 0.01 ** and p < 0.001 *** vs. wt/sham/Cont., p < 0.05 # and p < 0.001 ### vs. Cont Mcpt4-/-, p < 0.001 ¤¤¤ vs. Cont wt.