Table 1. Demographic and Clinical Characteristics by Treatment Group.

	Primary Enucleation, Patients (n=143)	Secondary Enucleation, Patients (n=60)	P-value
Sex
Male	82 (57.3%)	22 (36.7%)	0.009
Female	61 (42.7%)	38 (63.3%)
Laterality of tumor
Unilateral	128 (89.5%)	17 (28.3%)	<0.001
Bilateral	14 (9.8%)	43 (71.7%)
Age at diagnosis (months)
Median	24.0	9.0	<0.001
Range	1.0-108.4	0.3-72.6
Mean (SD)	27.7 (19.1)	12.1 (12.0)
	Primary Enucleation, Eyes (n=144)	Secondary Enucleation, Eyes (n=63)	P-value
Time to Enucleation (days)
Median	3	380	<0.001
Range	0-14	30-4775
Mean (SD)	3.6 (3.0)	566.0 (673.9)
Reese-Ellsworth Group
I	0	2	<0.001
II	0	5
III	2	8
IV	1	7
V	137	37
Not available	4	4
International Classification Group
A	0	0
B	1	13
C	1	7	<0.001
D	54	34
E	86	3
Not available	2	6
Vitreous tumor seeds
Yes	115	40	0.015
No	29	23
Subretinal tumor seeds
Yes	109	21	<0.001
No	35	41
Data not available	0	1
Retinal detachment
Yes	126	39	<0.001
No	18	23
Data not available	0	1