Table 3. Histopathologic Findings among Primarily or Secondarily Enucleated Eyes.
| Finding | Primary Enucleation, Eyes n=144 (%) | Secondary Enucleation, Eyes n=63 (%) | P-value |
|---|---|---|---|
| High-Risk histopathologic features | |||
| Yes | 46 (32%) | 13 (21%) | 0.132 |
| No | 98 (68%) | 50 (79%) | |
|
| |||
| Anterior chamber invasion | |||
| Yes | 8 (6%) | 3 (5%) | 1 |
| No | 136 (94%) | 60 (95%) | |
|
| |||
| Iris invasion | |||
| Yes | 9 (6%) | 4 (6%) | 1 |
| No | 135 (94%) | 59 (94%) | |
|
| |||
| Ciliary body invasion | |||
| Yes | 10 (7%) | 8 (13%) | 0.188 |
| No | 134 (93%) | 55 (87%) | |
|
| |||
| Choroid invasion | |||
| None | 63 (44%) | 45 (71%) | 0.005a |
| Minimal | 3 (2%) | 0 (0%) | |
| Focal | 46 (32%) | 14 (22%) | |
| Massive | 32 (22%) | 4 (6%) | |
|
| |||
| Optic nerve invasion | |||
| None | 23 (16%) | 45 (71%) | <0.001b |
| Prelaminar | 57 (40%) | 14 (22%) | |
| Laminar | 37 (26%) | 3 (5%) | |
| Postlaminar | 25 (17%) | 1 (2%) | |
| To cut Margin | 2 (1%) | 0 (0%) | |
|
| |||
| Scleral invasion | |||
| Yes | 18 (13%) | 7 (11%) | 1 |
| No | 126 (87%) | 56 (89%) | |
|
| |||
| Extraocular disease | |||
| Yes | 5 (3%) | 2 (3%) | 1 |
| No | 139 (97%) | 61 (97%) | |
a
Data reflects a comparison of massive choroid vs. none/minimal/focal choroid invasion.
b
Data reflects a comparison of postlaminar/to cut margin (postlaminar) vs. none/prelaminar/laminar optic nerve invasion.