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Kinetics of splenocyte proliferations. Splenocytes were incubated with the different stimuli (ConA, LPS, MBP-Hsp70, MBP-Nt70, and MBP-Hsp83 used at the concentrations described in Fig 1). [3H]-Thymidine incorporation (A) and viable cell numbers (B) were determined in the cultures on the indicated days. ConA, concanavalin A; LPS, lipopolysaccharide; MBP, maltose-binding protein; Hsp, heat shock protein; Nt, N-terminal domain
