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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Neuropharmacology. 2016 Oct 5;113(Pt A):231–240. doi: 10.1016/j.neuropharm.2016.10.003

Figure 5.

Figure 5

Fear conditioning decreases β3-AR facilitation of eIPSCs. A) Timecourse graph demonstrating that application of the β3-AR agonist, BRL37344 (10μM), potentiates evoked inhibitory post-synaptic current (eIPSC) amplitude in slices obtained from naïve animals and UP controls. B) Application of the β3-AR agonist BRL37344 facilitates LPC eIPSC amplitude in slices obtained from naïve (n = 6 cells/animals, p < 0.01) and UP animals (n = 6 cells/animals, p < 0.05), but this facilitation was abolished in slices taken from fear conditioned animals (n = 6 cells/animals, p > 0.05). C) The percent change in eIPSC amplitude in the presence of BRL37344 was greater in naïve and UP slices, as compared to slices taken from FC animals (p < 0.05).