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. Author manuscript; available in PMC: 2016 Dec 10.
Published in final edited form as: ACS Infect Dis. 2016 Oct 4;2(12):945–957. doi: 10.1021/acsinfecdis.6b00144

Figure 2.

Figure 2

Inhibitory activity of DSM421 on a panel of Plasmodium and mammalian DHODHs. A. Plasmodium enzymes. B. Mammalian enzymes. Triplicate data were collected per concentration point and data were fitted in GraphPad Prism to log(inhibitor) vs. response (three parameter equation) equation for the Plasmodium enzymes, and to the standard IC50 equation (v=vo/(1+(X/IC50)), where v is the enzyme velocity) for the mammalian enzymes. The fitted IC50 values with error estimates are shown in Tables 1 and 2. Error bars represent the standard deviation of the mean.