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. Author manuscript; available in PMC: 2017 Nov 15.
Published in final edited form as: Anal Chem. 2016 Oct 26;88(22):11147–11153. doi: 10.1021/acs.analchem.6b03307

Figure 1.

Figure 1

(A) Summary of the total intracellular metabolite concentrations for HK-2 (red), UOK-262 (blue), PANC-1 (yellow), and GIST-T1 (green) at 3 h of nonenriched glucose incubation. Acetate, alanine, aspartate, creatine, glycine, isoleucine, lactate, leucine, NAD+, threonine, tyrosine, valine, glutamate, and glutamine for the total intracellular pool size were accurately fitted as quantified. All metabolites are referenced to internal standard DSS (0.5 mM). (B) Summary of the baseline extracellular metabolite concentrations (culture media) for HK-2, UOK-262, PANC-1, and GIST-T1. A positive number of the plot refers to the net production of the metabolites of interest, whereas a negative number reflects the net consumption of the metabolites of interest calculated comparing to the preincubation media. Alanine, isoleucine, lactate, leucine, lysine, phenylalanine, threonine, tyrosine, valine, glutamine, and tryptophan for the extracellular pool size were analyzed.