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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Neuropharmacology. 2016 Oct 8;113(Pt A):198–205. doi: 10.1016/j.neuropharm.2016.10.005

Figure 4. CDPPB attenuated CIE-induced effects in extinction learning.

Figure 4

A) CIE exposure resulted in delayed extinction of ethanol-seeking behavior. Treatment with CDPPB prior to each extinction session reduced active lever responding on multiple days in both CIE-treated rats and in air-exposed controls. B) While CIE exposure increased the number of sessions to reach extinction criteria, CDPPB attenuated this deficit. Furthermore, CDPPB treatment also facilitated extinction learning in control (non-CIE) rats (#,* p < 0.05; * indicates a significant increase from controls; # indicates a significant decrease compared to respective controls).