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. Author manuscript; available in PMC: 2017 Nov 23.
Published in final edited form as: J Am Chem Soc. 2016 Nov 14;138(46):15157–15166. doi: 10.1021/jacs.6b06848

Figure 1.

Figure 1

Overview of reactivity-based screening strategy. (A) Reaction scheme for labeling aldehydes and ketones with dibrominated aminooxy probe 1. (B) Labeled compounds show a mass shift accompanied by a distinctive isotopic distribution by mass spectrometry, allowing straightforward identification of peaks of interest.