Fig 2.

(A) Adult male F344 rats (n = 4/group) either were exposed to 100, 5-second, 1.6-mA inescapable tail shocks (stress) or remained in their home cages (no stress). Blood samples were taken the day before the experimental procedure (baseline), after 25 tail shocks (25 minutes), after 100 tail shocks (100 minutes), and 2 hours after stressor termination. Time-matched blood samples were taken from nonstressed home cage controls animals, and eHsp72 was measured. (B) Rats (n = 16) either were exposed to inescapable tail shocks (stress) or remained in their home cages (no stress). Immediately after stressor termination, rats (n = 4/group) were injected either with E coli or with saline (vehicle). Two hours after E coli challenge and stress or no-stress treatment, rats were sacrificed, inflammatory tissue was harvested and placed in culture, and eHsp72 was measured. All figures represent mean ± standard error of the mean. (A) Stress vs no stress, F-PLSD *P < 0.05. (B) Stress (E coli) vs stress (vehicle), F-PLSD *P < 0.05