Table 1.

Sequential antibiotic treatments used in this study

Treatment	Antibiotic addition (h)		Abbreviation	Description
	0 h	8 or 12 h
1	No (0)	No (8)	CON	No first and second antibiotic addition
2	No (0)	1 MIC CIP (8)	CON-CIP	No initial antibiotic addition followed by 1 MIC ciprofloxacin addition
3	No (0)	1 MIC MER (8)	CON-MER	No initial antibiotic addition followed by 1 MIC meropenem addition
4	1/4 MIC CIP (0)	No (12)	1/4CIP-CON	Initial 1/4 MIC ciprofloxacin followed by no antibiotic addition
5	1/4 MIC CIP (0)	1 MIC CIP (12)	1/4CIP-CIP	Initial 1/4 MIC ciprofloxacin followed by 1 MIC ciprofloxacin addition
6	1/4 MIC CIP (0)	1 MIC MER (12)	1/4CIP-MER	Initial 1/4 MIC ciprofloxacin followed by 1 MIC meropenem addition

CON, CIP, and MER denote no antibiotic addition, ciprofloxacin, and meropenem, respectively