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. 2004 Aug 31;2(9):e268. doi: 10.1371/journal.pbio.0020268

Figure 3. Selection against Disruption of Predicted ESEs in Different Exon Regions.

Figure 3

Summary ORs were calculated for mutations that disrupt RESCUE-ESEs as in Figure 2, for each of four regions spanning the length of a typical human internal exon. The heights of the blue bars represent the odds that an ESE will be disrupted by a mutation in the set of 2,561 validated SNPs (selected mutations) relative to the odds of disruption in the set of 100,000 simulated (unselected) mutations. Error bars extend one standard deviation on either side of the calculated value.