Figure 4.

Effects of resveratrol (RES) on MnSOD enzyme activity and total β-catenin protein. PBMCs were treated with 50 µM RES for 12 h incubation. a) MnSOD enzyme activity was non-significantly increased in healthy subjects after treatment with RES. Also it was significantly increased in CAD patients after treatment with RES in comparison with blank. b) After treatment with RES a non-significant increasing trend was found for total β-catenin protein of healthy subjects compared to blank. Total β-catenin protein of CAD patients did not significantly increase after treatment with RES. c) Between-group differences showed higher MnSOD enzyme activitiy and total β-catenin protein levels for healthy subjects in comparison with CAD patients. RES was dissolved in DMSO, and blank groups (untreated cells) were containing only DMSO. In both blank and RES treated cells, DMSO was present at equal concentration (0.025%). All experiments were performed in duplicate, and the mean of duplicates were used for statistical analyses. Data are expressed as means ± SEM