Skip to main content
. Author manuscript; available in PMC: 2017 Dec 6.
Published in final edited form as: Structure. 2016 Dec 6;24(12):2163–2173. doi: 10.1016/j.str.2016.11.004

Figure 2. Rat Cbln1 binds Nrxn1β with high affinity and a stoichiometry of 1 hexamer to 1.

Figure 2

A. Isothermal titration calorimetry experiments for Cbln1. Molar ratio represents the ratio of Neurexin monomers to Cerebellin hexamers.

B–C. MALS analysis confirms molar mass for Cbln1 and Cbln1-Nrxn1β complex to match one hexamer (B), and one hexamer + one monomer (C), respectively.