Table 2.
Clinical and immunohistochemical characteristics of cases with a β-catenin mutation.
| Diagnosis | Age/gender | Procedure | β-catenin mutation |
GS staining pattern | β-catenin staining pattern |
|---|---|---|---|---|---|
| Hepatocellular adenoma, inflammatory with β-catenin activation |
33/F | Resection | T41A | Diffuse homogeneous | Nuclear |
| Hepatocellular adenoma, inflammatory with β-catenin activation |
32/F | Resection | T41A | Diffuse heterogeneous | Membranous |
| Atypical hepatocellular neoplasm | 26/M | Biopsy | T41A | Diffuse homogeneous | Membranous |
| Atypical hepatocellular neoplasm | 37/M | Resection | S35insN | Diffuse heterogeneous | Membranous |
| Atypical hepatocellular neoplasm | 36/M | Resection | T41A | Diffuse heterogeneous | Membranous |
| Hepatocellular carcinoma, non-cirrhotic |
71/M | Resection | S45P | Diffuse homogeneous | Nuclear |
| Hepatocellular carcinoma, cirrhotic | 65/M | Resection | S33C | Diffuse homogeneous | Nuclear |
| Hepatocellular carcinoma, cirrhotic | 59/M | Resection | T41A | Diffuse homogeneous | Nuclear |
| Hepatocellular carcinoma, cirrhotic | 63/M | Resection | T41A | Diffuse homogeneous | Nuclear |
| Hepatocellular carcinoma, non-cirrhotic |
36/M | Resection | T41A | Patchy | Membranous |
| Hepatocellular carcinoma, non-cirrhotic |
50/M | Biopsy | T41A | Diffuse heterogeneous | Membranous |
| Hepatocellular carcinoma, non-cirrhotic |
78/M | Resection | T41A | Diffuse heterogeneous | Nuclear |
| Hepatocellular carcinoma, cirrhotic | 66/M | Resection | S35insI | Diffuse homogeneous | Nuclear |
| Hepatocellular carcinoma, non-cirrhotic |
45/F | Resection | T41A | Diffuse heterogeneous | Nuclear |
| Hepatocellular carcinoma, cirrhotic | 59/F | Resection | S35_T41del | Patchy | Membranous |