Table 3.
Glutamine synthetase staining |
Typical hepatocellular adenoma (n=15) |
Atypical hepatocellular neoplasm (n=5) |
Hepatocellular carcinoma (n=60) |
|||
---|---|---|---|---|---|---|
β-catenin mutated (%) |
β-catenin nuclear (%) |
β-catenin mutated (%) |
β-catenin nuclear (%) |
β-catenin mutated (%) |
β-catenin nuclear (%) |
|
Patchy glutamine synthetase |
0/9 | 0/9 | 0/1 | 0/1 | 2/13 (15) | 0/13 |
Diffuse glutamine synthetase-all |
2/6 (33) | 2/6 (33) | 3/4 (75) | 0/4 | 8/47 (17) | 18/47 (38) |
Diffuse glutamine synthetase - homogeneous pattern only |
0/2 | 0/2 | 1/1 (100) | 0/1 | 5/19 (26) | 14/19 (74) |
Diffuse glutamine synthetase - heterogeneous pattern only |
2/4 (50) | 2/4 (50) | 2/3 (67) | 0/3 | 3/28 (11) | 4/28 (14) |