Table 1.
Demographic, clinical, and neuropsychological features of ALS patients and healthy control subjects (HCs; mean ± SD).
| Demographic and clinical parameters | ALS patients (n = 22) | HCs (n = 15) | F/χ2 | p |
|---|---|---|---|---|
| Age | 58.19 ± 9.63 | 55.4 ± 8.72 | 1.586 | 0.218 |
| Education (years) | 11.38 ± 4.55 | 9.93 ± 2.68 | 2.584 | 0.119 |
| Gender (M:F) | 13:9 | 8:7 | 0.120 | 0.729 |
| Disease duration∗ | 18.73 ± 10.87 | – | ||
| ALSFRS-R total score | 41 ± 3.86 | – | ||
| ALSFRS-R bulbar subscore | 10.45 ± 1.68 | – | ||
| ALSFRS-R arm subscore | 9.54 ± 2.1 | – | ||
| ALSFRS-R leg subscore | 9.18 ± 2.46 | – | ||
| ALSFRS-R respiratory subscore | 11.7 ± 0.7 | – | ||
| UMN score | 6.50 ± 4.68 | – | ||
∗Months from symptom onset to assessment. ALSFRS-R, amyotrophic lateral sclerosis functional rating scale; UMN, upper motor neuron.