Figure 5.

Identification of muscarinic receptor subtypes mediating effects of cholinomimetics. (A) [Ca²⁺]_i transients in the presence of muscarine (10 μM) and pirenzepine (100 nM). (B) Mean values of amplitude of [Ca²⁺]_i transients in the presence of muscarine and pirenzepine. (C) [Ca²⁺]_i transients in the presence of methoctramine (10 nM) and muscarine (10 μM). (D) Mean values of amplitude of [Ca²⁺]_i transients in the presence of methoctramine (10 nM) and muscarine (10 μM). Abbreviations: Pirenz, pirenzepine; Musc, muscarine; Methoct, methoctramine. ^*P < 0.05 vs. control; n = 5.