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. 2016 Dec 12;7:621. doi: 10.3389/fphys.2016.00621

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Copyright © 2016 Khaziev, Samigullin, Zhilyakov, Fatikhov, Bukharaeva, Verkhratsky and Nikolsky.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of nicotinic receptor subtypes mediating effects of cholinomimetics. Mean values of magnitude of [Ca²⁺]_i transients in the presence of different concentrations (they are indicated in brackets) of mecamylamine blocking various subtypes of nicotinic receptors and after addition of nicotine (10 μM); in the presence of metillikakonitin (10 nM) and after addition of nicotine (10 μM). Abbreviations: Nic, nicotine; Mecam, mecamylamine. MLA, metillikakonitin. Control corresponds to 100%. ^*P < 0.05 vs. control saline; n = 3–6.