Fig. 2.

In vitro transduction of miR-132 in CRC cells. a MiR-132-transfected cells demonstrated significantly slower growth rate than negative control-transfected cells. b Colony formation assay showed that miR-132 overexpression resulted in significant inhibition of tumor growth. c MiR-132 overexpression markedly reduced invasion ability compared to negative control. In contrast, miR-132 inhibitor increased invasion ability. Data are presented as mean ± SD. NC negative control-transfected cells, mimic miR-132 miR-132-transfected cells, inhibitor miR-132 inhibitor miR-132-transfected cells. *P < 0.05