Table III.

The distribution of the categories of functional impairment measured with the Lequesne index at the subsequent visits

Visit	Functional impairment						Stuart-Maxwell test with Bonferroni correction
	No impairment (%)	Mild (%)	Moderate (%)	Severe (%)	Very severe (%)	Extremely severe (%)	Sequentially			vs. visit 0
0	1.60	20.04	22.65	21.33	19.35	15.03	p < 0.001	–	–	–
1	3.92	30.41	24.25	22.62	13.16	5.64		p < 0.001	–	p < 0.001
2	7.38	38.68	26.45	16.70	7.41	3.39	–		p < 0.001	p < 0.001
3	11.63	44.19	26.04	11.25	4.73	2.15	–	–		p < 0.001