. 2016 Nov 28;2016:9161648. doi: 10.1155/2016/9161648

Table 1.

MNPCE frequencies from dams of rat study groups at different sampling times.

Groups	0 h	24 h	48 h	72 h	96 h	120 h
Negative control	1.40 ± 0.89	1.80 ± 1.30	1.80 ± 0.84	1.60 ± 1.14	2.00 ± 1.30	2.20 ± 1.30
Negative control	1.40 ± 0.89	^∗NS	^∗NS	^∗NS	^∗NS	^∗NS

CP lower-dose	1.20 ± 0.83 ^∗∗NS	4.47 ± 1.45	13.47 ± 3.53	12.07 ± 3.61	7.33 ± 3.48	2.53 ± 1.12
		^∗ P = 0.024	^∗ P = 0.003	^∗ P = 0.005	^∗ P = 0.029	^∗NS
		^∗∗ P = 0.043	^∗∗ P = 0.006	^∗∗ P < 0.001	^∗∗NS	^∗∗NS

CP middle-dose	1.60 ± 0.89 ^∗∗NS	3.47 ± 1.61	20.60 ± 4.34	13.40 ± 3.58	14.07 ± 4.75	2.07 ± 0.86
		^∗NS	^∗ P < 0.001	^∗ P = 0.002	^∗ P = 0.007	^∗NS
		^∗∗NS	^∗∗ P = 0.002	^∗∗ P = 0.005	^∗∗ P = 0.018	^∗∗NS

CP higher-dose	1.27 ± 0.43 ^∗∗NS	6.73 ± 2.12	24.33 ± 5.25	20.20 ± 6.21	16.80 ± 4.27	3.60 ± 1.38
		^∗ P = 0.006	^∗ P = 0.001	^∗ P = 0.003	^∗ P = 0.002	^∗ P = 0.033
		^∗∗ P = 0.003	^∗∗ P = 0.002	^∗∗ P < 0.001	^∗∗ P = 0.005	^∗∗NS

COL lower-dose	1.00 ± 0.71 ^∗∗NS	3.00 ± 0.71	5.00 ± 1.87	7.60 ± 2.40	7.20 ± 1.64	3.00 ± 1.22
		^∗ P = 0.011	^∗ P = 0.025	^∗ P = 0.007	^∗ P = 0.003	^∗ P = 0.022
		^∗∗NS	^∗∗NS	^∗∗ P = 0.014	^∗∗ P = 0.003	^∗∗NS

COL middle-dose	1.20 ± 0.45 ^∗∗NS	3.80 ± 1.79	7.00 ± 1.22	7.60 ± 2.51	6.00 ± 2.55	3.20 ± 0.84
		^∗ P = 0.033	^∗ P = 0.001	^∗ P = 0.003	^∗ P = 0.009	^∗ P = 0.011
		^∗∗NS	^∗∗ P = 0.001	^∗∗ P = 0.016	^∗∗NS	^∗∗NS

COL higher-dose	1.20 ± 0.84 ^∗∗NS	3.60 ± 1.52	5.80 ± 1.92	6.40 ± 2.40	6.40 ± 2.41	3.60 ± 1.82
		^∗ P = 0.024	^∗ P = 0.006	^∗ P = 0.014	^∗ P = 0.012	^∗NS
		^∗∗NS	^∗∗ P = 0.031	^∗∗ P = 0.036	^∗∗NS	^∗∗NS

AraC lower-dose	1.20 ± 0.84 ^∗∗NS	3.80 ± 1.79	9.20 ± 2.38	8.00 ± 2.74	3.60 ± 0.89	1.80 ± 0.45
		^∗ P = 0.041	^∗ P = 0.002	^∗ P = 0.003	^∗ P = 0.024	^∗NS
		^∗∗NS	^∗∗ P = 0.006	^∗∗ P = 0.009	^∗∗NS	^∗∗NS

AraC middle-dose	1.20 ± 1.10 ^∗∗NS	5.60 ± 1.82	8.80 ± 2.39	7.80 ± 1.30	5.80 ± 1.30	3.40 ± 1.52
		^∗ P = 0.022	^∗ P = 0.006	^∗ P = 0.003	^∗ P = 0.006	^∗NS
		^∗∗ P = 0.013	^∗∗ P = 0.008	^∗∗ P < 0.001	^∗∗ P = 0.006	^∗∗NS

AraC higher-dose	1.40 ± 0.89 ^∗∗NS	7.40 ± 2.07	9.00 ± 2.00	8.20 ± 2.49	8.00 ± 2.00	3.40 ± 1.51
		^∗ P = 0.001	^∗ P = 0.002	^∗ P = 0.003	^∗ P = 0.001	^∗ P = 0.047
		^∗∗ P = 0.001	^∗∗ P = 0.003	^∗∗ P = 0.010	^∗∗ P = 0.005	^∗∗NS

Data (‰) expressed as mean ± standard deviation per group of MNPCEs/1,000 PCEs. MNPCEs: micronucleated polychromatic erythrocytes, PCEs: polychromatic erythrocytes, h: hours, and NS: not significant. ^∗Intragroup comparisons. ^∗∗Intergroup comparisons between negative control groups versus the other groups.