Table 1.
| Literature | Age, sex |
Diagnosis | FNA | Dimensions in cm; extrathyroidal unless specified | Weight | Symptoms | PTH level in pg/mL | Initial calcium in mg/dL | Treatment |
|---|---|---|---|---|---|---|---|---|---|
| Kovacs et al. 1994 [4] | 48 M | US | NA | NA | NA | NA | 43 | 10.8 | Right hemithyroidectomy and total parathyroidectomy |
| Grenko et al. 1995 [5] | 40 M | NA | NA | 5 × 3 × 1.5 | 7.6 g | Fatigue, leg cramps | 945 | 11.3 | Parathyroidectomy |
| Bégueret et al. 1999 [14] | 73 M | NA | NA | 2.8 × 1 cm | NA | Nephrolithiasis | 207 | 13.7 | NA |
| Dundar et al. 2001 [13] | 43 F | (+) US/(+) sestamibi scan | NA | 6; intrathyroidal | NA | Fractures, cramps, fatigue | 1667 | 13.3 | Left total and right near total thyroidectomy |
| Kuhel et al. 2001 [15] | 56 F | (+) US/(−) sestamibi scan | FNA colloid nodule | Right 2.8 Left 1.5 |
1.7 g 0.5 g |
Asymptomatic | 52 | 13.2 | Parathyroidectomy, R thyroid lobectomy, and isthmectomy |
| Kanda et al. 2004 [2] | 52 F | (+) US/(+) sestamibi scan | NA | 6.8 × 2.8 × 1.9 | 15.4 g | Gastritis, nephrolithiasis | 672 | 10.7 | Parathyroidectomy |
| Prasad et al. 2004 [16] | 40 F | (+) US | NA | 3 × 1.5 × 1.0 | 4.2 g | Fatigue, cramps, weakness | 346 | 12.4 | Parathyroidectomy |
| Kodama et al. 2007 [17] | 18 F | (+) US/(+) sestamibi scan | NA | 5 × 3.3 × 3 | 21.7 g | Renal stones | 356 | 11.6 | Parathyroidectomy |
| Papanicolau-Sengos et al. 2011 [1] | 64 M | (+) CT chest with contrast | Follicular neoplasm of the thyroid | 4.7 × 3.5 × 1.7 | NA | Asymptomatic | NA | NA | Parathyroidectomy |
| Chou et al. 2014 [7] | 81 F | (+) US/(+) sestamibi scan | NA | 3.8 | NA | Hyper/pancreatitis | 450 | 12.0 | Parathyroidectomy |
| Bai et al. 2012 [18] | 81 M | (−) US/(+) sestamibi scan | NA | 4 × 2.5 × 1.6 | 6.91 g | NA | 211 | NA | Parathyroidectomy |
| Bai et al. 2012 [18] | 55 M | (−) US/(−) sestamibi scan | Concomitant papillary thyroid carcinoma | 1.4 × 0.8 × 0.6 | 0.27 g | NA | 151 | NA | Thyroidectomy, right neck lymph node dissection, and parathyroidectomy |
| Piggott et al. 2013 [8] | 74 F | (+) US/(+) sestamibi scan | NA | 5.5 × 2.5 × 2 | 13 g | Abdominal pain, constipation, lethargy | 489 | 12.5 | Parathyroidectomy |
| Ezzat et al. 2013 [10] | 73 M | (+) US/(+) sestamibi scan | NA | 3.7 × 3.5 × 1.7 | 8 g | NA | 293 | 13.0 | Parathyroidectomy |
| Ezzat et al. 2013 [10] | 74 F | (+) US/(−) sestamibi scan | NA | 1.6 × 1.2 × 0.3 | 0.9 g | NA | 112 | 11.6 | Parathyroidectomy |
| Tassone et al. 2014 [9] | 54 F | (+) US/(−) sestamibi scan | NA | 2.8 × 1.1 × 1.1 | NA | Hyper/bone pain, depression, forgetfulness | 130 | 12.4 | Parathyroidectomy |
| Murakami et al. 2014 [19] | 59 F | (+) US/(+) CT chest/(−) sestamibi scan | NA | NA; extrathyroidal | 0.5 g | Renal stones, bone fracture | 72 | 11.9 | Parathyroidectomy |
| Current case | 34 F | (+) US | Thyroid follicular cells without atypia | 2.5 × 1.7 × 1.5 intrathyroidal | NA | Asymptomatic | NA | 9.3 | Thyroidectomy |
NA: not available; (+): positive; (−): negative; sestamibi scan: sestamibi scan of the parathyroid; US: US of the thyroid.