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PARP1 is colocalized with LANA. Anti-PARP1 (Alexa 546, red), anti-LANA (Alexa 488, green), and DAPI (blue) were used to stain nuclei, and merged images are also shown for each case. All of the data were obtained with a Zeiss 510 laser confocal fluorescent microscope. BC3 cells (A), BJAB cells (B), and 293 cells (C) expressing LANA and containing multiple copies of BAC TR-2, a TR-containing bacterial artificial chromosome construct.
