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The lineage of the family with complete heart block indicated by the dark symbol, females by circles, and males by squares. Letters (a) and (b) indicate genotypes of 2 variants in the SCN5A gene for c.101G>A and c.3832G>A. The homozygous reference genotypes are indicated by (−/−) and heterozygous alternate genotypes by (−/+). The genotypes of II-1 are presumed genotypes which are inferred from his children.
