Table 2.
Comparison of neoplastic behaviors in patients with MTC according to RET mutation status.
| RET mutation (n) | Positive (5) | Negative (14) | p |
|---|---|---|---|
| Age at diagnosis (years) | 38.4 ± 20.2 | 54.6 ± 11.8 | 0.04 |
| Tumor diameter (cm) | 1.48 ± 1.1 | 2.37 ± 1.6 | 0.61 |
| Vascular invasion | 20% | 28.6% | 0.71 |
| Nodal metastases at surgery | 60% | 57% | 0.66 |
| Distant metastases | 20% | 14% | 0.87 |
| Surgical reintervention because of MTC recurrence | 40% | 35.7% | 0.76 |
RET: REarranged during Transfection. MTC: medullary thyroid carcinoma.