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Quantification of TIMP1 and TIMP2 mRNA levels. (a) One week after MI, small increases in TIMP1 mRNA levels were observed. (c) After four weeks, significant increases were seen in both infarct and border regions of the Empty Bead group. (b) After one week, no significant differences were observed in TIMP2 mRNA levels; however four weeks after MI, significantly more mRNA was detected in the infarct and border zone of the Beads group (d). N = 3–5 per group; P < 0.05.
