Table 3.
CA1 microglial numbers from pyramidal cell layer from animals injected with normal brain homogenate (NBH) or NBH followed by Piry intranasal injection or with ME7 infected brain homogenate (ME7) or by ME7 followed by Piry virus intranasal injection.
| Stratum pyramidale of CA1 | |||
|---|---|---|---|
| Subjects | N | Thickness (μm) | CE (Scheaffer) |
| NBH | |||
| NBHVII-2 | 3681 | 28.5 | 0.05 |
| NBHVII-3 | 2200 | 19.2 | 0.06 |
| NBHVII-4 | 3357 | 19.2 | 0.05 |
| Mean | 3080 | 22.3 | 0.05 |
| SD | 779 | ||
| CV2 | 0.064 | ||
| CE2 | 0.003 | ||
| CE2/CV2 | 0.041 | ||
| CVB2 | 0.061 | ||
| CVB2 (% CV2) | 95.9 | ||
|
| |||
| NBH+VIRUS | |||
| NBHV-3 | 3412.64 | 18.7 | 0.04 |
| NBHVI-1 | 2506.66 | 15.1 | 0.05 |
| NBHVI-2 | 2094.18 | 18.2 | 0.05 |
| NBHVI-4 | 3634.26 | 18.1 | 0.05 |
| Mean | 2912 | 17.5 | 0.05 |
| SD | 732 | ||
| CV2 | 0.063 | ||
| CE2 | 0.002 | ||
| CE2/CV2 | 0.035 | ||
| CVB2 | 0.061 | ||
| CVB2 (% CV2) | 96.5 | ||
|
| |||
| ME7 | |||
| ME7IX-1 | 5631 | 22.5 | 0.04 |
| ME7IX-4 | 4749 | 15.9 | 0.04 |
| ME7X-2. | 5625 | 20 | 0.04 |
| ME7X-4 | 3507 | 24.1 | 0.05 |
| Mean | 4878 | 21 | 0.04 |
| SD | 1003 | ||
| CV2 | 0.042 | ||
| CE2 | 0.002 | ||
| CE2/CV2 | 0.045 | ||
| CVB2 | 0.040 | ||
| CVB2 (% CV2) | 95.5 | ||
|
| |||
| ME7+VIRUS | |||
| ME7VII-1 | 10834 | 22.1 | 0.04 |
| ME7VII-4 | 7375 | 15.3 | 0.03 |
| ME7VIII-1 | 10240 | 23.8 | 0.04 |
| ME7VIII-4 | 6202 | 20.5 | 0.04 |
| Mean | 8663 | 20.4 | 0.04 |
| SD | 2230 | ||
| CV2 | 0.066 | ||
| CE2 | 0.001 | ||
| CE2/CV2 | 0.022 | ||
| CVB2 | 0.065 | ||
| CVB2 (% CV2) | 97.8 | ||
(∗)CVB2 = CV2 − CE2 (CV, coefficient of variation; CE, Scheaffer coefficient of error; CVB, biological variation coefficient).