Figure 2.

Stepwise variable selection by PLSDA allows separation of neutralization groups with combined T cell and myeloid cell data. (a) F-ratios for each individual variable are shown (n=41). (b) Iterative model testing shows ranking of immune variables by F-ratio for 10 iterations with 10 different random subsets of the cohort (n=31 per iteration). Model test iterations are shown from left to right (top), and variable ranking based on F-ratio from 1to 10 are shown from top to bottom. (c) PLSDA was performed including three top variables, and separation of subjects are shown in Tukey box and whiskers plots with group medians for VC subjects (n=41). (d) PLSDA was performed including three top variables. Graph shows separation of subjects by combined variable score on the y-axis by neutralization breadth <5 versus ≥breadth.