TABLE 6.
Ion-pair networks formed between ICAM-1 and HRVsa
| Ion-pair group | Residue(s) of ICAM-1 | HRV14
|
HRV16
|
||
|---|---|---|---|---|---|
| Residue | Electrostatic potential energy (kcal/mol) of group | Residue | Electrostatic potential energy (kcal/mol) of group | ||
| A | Asp26, Asp71 | Lys1280 | Arg1277 | ||
| Lys1283 | |||||
| Lys3089 | |||||
| Asp3093 | His3092 | ||||
| Lys3231 | |||||
| −180.4 | −250.0 | ||||
| B | Lys29 | His1220 | Arg1205 | ||
| Asp1213 | |||||
| Asp3177 | |||||
| Asp3179 | Asp3181 | ||||
| −117.5 | −95.5 | ||||
| C | Glu34, Lys77 | Glu1210 | |||
| Lys2143 | |||||
| Glu2163 | |||||
| Lys2164 | |||||
| −160.3 | −106.1 | ||||
| D | Glu41, Lys50 | Lys1103 | |||
| Glu3236 | |||||
| −127.3 | −16.4 | ||||
a
Equivalent HRV14 and HRV16 residues are aligned. Electrostatic potential energies for each group of interactions are shown.