Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Processivity of the wild-type and mutant RTs. As described in Materials and Methods, a 5′ end-labeled primer was annealed to single-stranded M13mp18 DNA and then extended with wild-type HIV-1 RT or an RT variant in the presence of a 10.0 μM concentration of each dNTP and unlabeled poly(rC) · oligo(dG). The cold trap limits extension to one round of polymerization. The location of the size marker bands is shown on the left.
