Table 2. Echocardiographic analysis of CO, carotid artery resistance and left ventricle mass of Efnb3 KO and WT mice.
Mouse Type | Age | Cardiac output (ml/min) | Left Carotid PI | Right Carotid PI | LV Mass (mg) |
---|---|---|---|---|---|
Echocardiographic parameters of male Efnb3 KO mice | |||||
KO male | 15wk | 14.65 | 0.75 | 0.72 | 103.7 |
KO male | 15wk | 21.46 | 0.87 | 0.68 | 125.8 |
KO male | 15wk | 24.79 | 0.73 | 0.78 | 154.1 |
KO male | 15wk | 17.23 | 0.74 | 0.70 | 91.7 |
KO male | 15wk | 14.93 | 0.78 | 0.78 | 89.7 |
KO male | 14wk | 18.2 | 0.73 | 0.72 | 133.6 |
KO mean | 18.54 | 0.77 | 0.73 | 116.4 | |
SD | 3.939 | 0.0533 | 0.041 | 25.65 | |
WT male | 14wk | 21.5 | 0.83 | 0.84 | 116.0 |
WT male | 15wk | 15.33 | 0.74 | 0.70 | 140.5 |
WT male | 15wk | 23.52 | 0.75 | 0.77 | 115.6 |
WT male | 15wk | 18.21 | 0.73 | 0.72 | 133.6 |
WT male | 14wk | 31.85 | 0.77 | 0.86 | 115.0 |
WT male | 14wk | 28.57 | 0.77 | 0.81 | 145.1 |
WT male | 14wk | 24.19 | 0.74 | 0.76 | 152.7 |
WT male | 14wk | 30.95 | 0.79 | 0.83 | 175.6 |
WT mean | 24.265 | 0.77 | 0.78 | 126.4 | |
SD | 5.92 | 0.030 | 0.047 | 12.57 | |
p value (t test) | 0.0637 | 0.9075 | 0.08200 | 0.4967 | |
Echocardiographic parameters of female Efnb3 KO mice | |||||
KO female | 15wk | 21.89 | 0.75 | 0.78 | 112.3 |
KO female | 15wk | 16.29 | 0.77 | 0.8 | 92.5 |
KO female | 14wk | 20.16 | 0.81 | 0.81 | 121.1 |
KO female | 15wk | 27.57 | 0.76 | 0.77 | 143.3 |
KO female | 15wk | 20.54 | 0.94 | 0.76 | 130.5 |
KO female | 14wk | 27.71 | 0.75 | 0.73 | 134.3 |
KO female | 15wk | 19.13 | 0.8 | 0.77 | 135.8 |
KO female | 14wk | 18.38 | 0.81 | 0.82 | 122 |
KO mean | 21.45 | 0.79 | 0.78 | 123.9 | |
SD | 4.153 | 0.062 | 0.029 | 16.04 | |
WT female | 14wk | 33.49 | 0.72 | 0.72 | 109 |
WT female | 14wk | 18.92 | 0.69 | 0.67 | 118.1 |
WT female | 14wk | 29.03 | 0.71 | 0.8 | 110.9 |
WT female | 14wk | 28.06 | 0.81 | 0.79 | 95.9 |
WT female | 14wk | 15.96 | 0.68 | 0.76 | 114.6 |
WT female | 14wk | 22.46 | 0.7 | 0.74 | 72.2 |
WT mean | 24.65 | 0.71 | 0.74 | 93.4 | |
SD | 6.664 | 0.047 | 0.048 | 29.98 | |
p value (t test) | 0.289 | 0.0218 | 0.132 | 0.0397 |
BP-related echocardiographic parameters of individual Efnb3 KO and WT mice are reported. Means ± SD are shown at the end of each group, and p values (unpaired one-way Student’s t test) are indicated at the bottom of Tables 2. PI: Pourcelot index; LV: left ventricle.