Table 2. Mean volumes (mL) and volume ratios (%) of CSF and brain parenchyma.
iNPH (52) | sNPH (15) | Control (31) | P1 | P2 | P3 | |
---|---|---|---|---|---|---|
Total intracranial spaces | 1517 ± 156 | 1467 ± 147 | 1487 ± 138 | 0.310 | 0.369 | 0.639 |
Brain parenchyma | 1096 ± 119 (72.4%) | 1177 ± 134 (80.3%) | 1154 ± 147 (77.5%) | 0.061 | 0.017 | 0.746 |
Total CSF | 420.4 ± 84.7 (27.6%) | 290.0 ± 85.2 (19.7%) | 333.1 ± 94.0 (22.5%) | <0.001 | <0.001 | 0.075 |
Total ventricles | 160.8 ± 45.2 (10.6%) | 121.4 ± 26.8 (8.2%) | 61.3 ± 31.9 (4.2%) | 0.002 | <0.001 | <0.001 |
Bilateral ventricles | 152.9 ± 41.7 | 112.2 ± 26.7 | 52.1 ± 26.4 | <0.001 | <0.001 | <0.001 |
Third ventricle | 5.3 ± 1.5 | 5.2 ± 1.2 | 3.5 ± 1.3 | 0.982 | <0.001 | <0.001 |
Fourth ventricle | 4.1 ± 2.0 | 4.5 ± 1.1 | 2.8 ± 1.5 | 0.181 | 0.002 | <0.001 |
Total subarachnoid spaces | 259.6 ± 71.5 (17.1%) | 168.4 ± 72.3 (11.5%) | 271.7 ± 85.7 (18.3%) | <0.001 | 0.569 | <0.001 |
Convexity subarachnoid space | 76.4 ± 35.4 | 73.0 ± 35.9 | 125.8 ± 54.8 | 0.758 | <0.001 | <0.001 |
Basal cistern and Sylvian fissure | 120.4 ± 32.7 | 51.6 ± 35.0 | 90.7 ± 34.0 | <0.001 | <0.001 | 0.001 |
Posterior fossa | 62.8 ± 17.7 | 43.9 ± 10.2 | 55.2 ± 19.7 | <0.001 | 0.057 | 0.038 |
P1; probability value of iNPH vs. sNPH for the Mann-Whitney-Wilcoxon test.
P2; probability value of iNPH vs. control for the Mann-Whitney-Wilcoxon test.
P3; probability value of sNPH vs. control for the Mann-Whitney-Wilcoxon test.