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. 2016 Dec 12;6:39070. doi: 10.1038/srep39070

Table 2. Mean volumes (mL) and volume ratios (%) of CSF and brain parenchyma.

  iNPH (52) sNPH (15) Control (31) P1 P2 P3
Total intracranial spaces 1517 ± 156 1467 ± 147 1487 ± 138 0.310 0.369 0.639
Brain parenchyma 1096 ± 119 (72.4%) 1177 ± 134 (80.3%) 1154 ± 147 (77.5%) 0.061 0.017 0.746
Total CSF 420.4 ± 84.7 (27.6%) 290.0 ± 85.2 (19.7%) 333.1 ± 94.0 (22.5%) <0.001 <0.001 0.075
Total ventricles 160.8 ± 45.2 (10.6%) 121.4 ± 26.8 (8.2%) 61.3 ± 31.9 (4.2%) 0.002 <0.001 <0.001
Bilateral ventricles 152.9 ± 41.7 112.2 ± 26.7 52.1 ± 26.4 <0.001 <0.001 <0.001
Third ventricle 5.3 ± 1.5 5.2 ± 1.2 3.5 ± 1.3 0.982 <0.001 <0.001
Fourth ventricle 4.1 ± 2.0 4.5 ± 1.1 2.8 ± 1.5 0.181 0.002 <0.001
Total subarachnoid spaces 259.6 ± 71.5 (17.1%) 168.4 ± 72.3 (11.5%) 271.7 ± 85.7 (18.3%) <0.001 0.569 <0.001
Convexity subarachnoid space 76.4 ± 35.4 73.0 ± 35.9 125.8 ± 54.8 0.758 <0.001 <0.001
Basal cistern and Sylvian fissure 120.4 ± 32.7 51.6 ± 35.0 90.7 ± 34.0 <0.001 <0.001 0.001
Posterior fossa 62.8 ± 17.7 43.9 ± 10.2 55.2 ± 19.7 <0.001 0.057 0.038

P1; probability value of iNPH vs. sNPH for the Mann-Whitney-Wilcoxon test.

P2; probability value of iNPH vs. control for the Mann-Whitney-Wilcoxon test.

P3; probability value of sNPH vs. control for the Mann-Whitney-Wilcoxon test.