Pressure overload disturbed protein folding in normal hearts. (A) A typical recording of the right carotid artery (A.) blood pressure (BP) of a rat before and after abdominal aortic banding. (B) Expression of HSP70, BiP, CHOP, XBP-1 (s, spliced form; u, unspliced form), and troponin T in hearts from rats 6 to 72 h after banding or from a rat 72 h after a sham operation was evaluated by Western blotting.