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Compound 1c activity in THP-1 intracellular activity and cytotoxicity assays
| Compound | Series | INH-R1 IC50, µM | INH-R1 IC90, µM | INH-R1 MIC, µM | INH-R2 IC50, µM | INH-R2 IC90, µM | INH-R2 MIC, µM | RIF-R2 IC50, µM | RIF-R2 IC90, µM | RIF-R2 MIC, µM |
| Compound 1c | 1–3 | 11.9 | 27 | 24.5 | 12 | 22 | 24 | 12 | 22 | 24 |
