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. 2016 Nov 18;113(49):14121–14126. doi: 10.1073/pnas.1616697113

Fig. 2.

Fig. 2.

MYC ESE eRNA expression depends on BRD4 and EBNA2. (A) Twenty-four hours after 500 nM JQ1 or vehicle treatment of LCLs, qRT-PCR was used to quantitate MYC ESE eRNAs. RNA levels were first normalized with GAPDH. MYC ESE eRNA levels were shown relative to control TFF1 eRNA, which was set to 1. Error bar indicated SD of triplicate data from three independent experiments. Student's t test, *P < 0.01. (B) Total RNA was extracted from conditional EBNA2HT LCLs, grown under permissive (E2+) or nonpermissive (E2-) conditions for 72 h, and the RNA expression levels were measured by qRT-PCR. RNA levels were first normalized to GAPDH. MYC ESE eRNA levels were shown relative to control TFF1 eRNA, which was set to 1. Error bar indicated SD of triplicate data from three independent experiments. Student's t test, *P < 0.01.