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. 2004 Sep;24(18):8210–8220. doi: 10.1128/MCB.24.18.8210-8220.2004

FIG. 8.

FIG. 8.

A model for the determination of chromatin structure. A map of the 102B region is shown, with the smallest and largest rightward deletions that result in a switch from the variegating 39C-12 transgene to a red-eye phenotype indicated as demarcating a euchromatic domain. Heterochromatic domains appear to be initiated from 1360 elements (shown as bars below the map), presumably targeted by the RNAi mechanism, localizing HP1 association with concomitant H3 modification for K9 methylation. Euchromatic domains may be initiated from regions having a high concentration of histone acetyltransferase activity. Both configurations can spread until stopped by competition.

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