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. 2016 Dec 12;6:38695. doi: 10.1038/srep38695

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Time-course of mean URs in striatum, thalamus and midbrain at different time points in normal, MDMA and DM+MDMA groups. (b) URs of [¹²³I]-ADAM SPECT during 210–240 min post-injection in various brain regions of normal, MDMA DM+MDMA groups at 24 months. These results are presented as mean ± S.D. *P < 0.05. compared with normal group; ^#P < 0.05. compared with MDMA group. (c) URs of [¹²³I]-ADAM SPECT during 210–240 min. in various brain regions of normal, MDMA and DM+MDMA groups at 30 months. These results are presented as mean ± S.D. *P < 0.05. compared with normal group; ^#P < 0.05. compared with MDMA group.