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. 2004 Sep;24(18):7949–7957. doi: 10.1128/MCB.24.18.7949-7957.2004

FIG. 3.

FIG. 3.

E. coli and LPS challenges of PGRP-L-deficient mice. (A) Ten wild-type or PGRP-L-deficient animals were injected intraperitoneally with 2 million (left panel) or 5 million (right panel) live E. coli bacteria and were monitored for 5 days. Survival is plotted against time in days. (B) Three wild-type or PGRP-L-deficient animals were injected intraperitoneally with 2 million E. coli bacteria. Serum IL-6 and TNF-α levels were determined by ELISA 90 min after injection. (C) Ten wild-type or PGRP-L-deficient (KO) mice were injected intraperitoneally with 2 mg of LPS and were monitored for 10 days. Survival is plotted against time in days.