. 2016 Nov 14;59(23):10788–10793. doi: 10.1021/acs.jmedchem.6b01110

Table 1. Ligand–Target Residence Times τ Obtained by Ligand-Observed ¹H-CPMG-RD Experiments, 600 MHz, 25 °C, and Relevant Complex Dissociation Constants (K_d).

ligand	resonance	target	τ [ms]	K_d [μM]
indoxyl sulfate	¹H-2	BSA	0.67 ± 0.09	30³⁴
proflavin	¹H-4/5	trypsin	0.19 ± 0.02	140³⁵
proflavin	¹H-9	trypsin	0.20 ± 0.03	140³⁵
isoquercitrin	¹H-6	Bet v 1a	1.0 ± 0.1	n/a
preQ₁	¹H-8	Fsu apt.	0.63 ± 0.08	0.28³⁶
preQ₁	¹H-8	TTe apt.	0.23 ± 0.03	0.002³⁷

Table 1. Ligand–Target Residence Times τ Obtained by Ligand-Observed 1H-CPMG-RD Experiments, 600 MHz, 25 °C, and Relevant Complex Dissociation Constants (Kd).