Table 1. P450 Isoforms That Catalyze Formation of Major Metabolite.
P450 isoform | major metabolite 2a (%), t = 2 h |
---|---|
1A2 | 0.6 |
2A6 | 2.5 |
2B6 | 0.1 |
2C9 | 4.9 |
2C18 | 1.3 |
2C19 | 1.1 |
2J2 | 1.1 |
3A4 | 1.3 |
P450 isoform | major metabolite 2a (%), t = 2 h |
---|---|
1A2 | 0.6 |
2A6 | 2.5 |
2B6 | 0.1 |
2C9 | 4.9 |
2C18 | 1.3 |
2C19 | 1.1 |
2J2 | 1.1 |
3A4 | 1.3 |