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Immunohistochemistry of the embryonic (E13.5 and E17.5) intestine of Y1062F knock-in mice. In wild-type embryos, ENS progenitors were stained with antiperipherin antibody in a ring-like fashion (A and C). In homozygous mutant embryos, positive cells were undetectable (B) or few (arrowheads in panel D). Bars, 50 μm.
