. 2016 Oct 3;7(12):1082–1086. doi: 10.1021/acsmedchemlett.6b00292

Table 1. mGluR5 PAM Potency, Fold Shift, Metabolic Stability, and Fsp³ Data for Selected 1H-Pyrazolo[3,4-b]pyridines.

Values represent mean of n ≥ 2 replicates.

Percentage remaining after 10 min incubation with human or mouse liver microsomes.¹⁷

Table 1. mGluR5 PAM Potency, Fold Shift, Metabolic Stability, and Fsp3 Data for Selected 1H-Pyrazolo[3,4-b]pyridines.