Table 2. In vitro culture of bone marrow stromal cells and splenocytes.
No. of osteoblast progenitors in bone marrow
|
No. of osteoclast-like cells
|
|||
---|---|---|---|---|
Exp. | Genotype | In bone marrow | In spleen | |
1 | Wild type | 20 ± 1.7 | 177 ± 12.8 | 128 ± 14 |
Fgfr2cC342Y/+ | 36 ± 3.4* | 205 ± 4 | 127 ± 7.4 | |
2 | Wild type | 11 ± 1.6 | 148 ± 6 | 91 ± 0.7 |
Fgfr2cC342Y/+ | 32 ± 1.4* | 150 ± 10.1 | 102 ± 9.5 |
Two independent experiments were conducted. *, P < 0.05 compared with wild type.