Table 2.

Organ drug distribution from various formulations

	Time (h)	Percent dose recovered
		Liver	Kidney	Lung	Spleen
Rifampicin drug solution	2	24.3 ± 0.3	7.5 ± 0.2	3.6 ± 0.7	2.4 ± 0.3
	4	32.7 ± 0.5	8.8 ± 0.7	4.9 ± 0.4	3.2 ± 0.2
	6	23.1 ± 0.2	6.5 ± 0.6	2.9 ± 0.4	1.6 ± 0.5
	24	7.6 ± 0.5	3.1 ± 0.2	Nil	Nil
Uncoupled SLNs	2	28.4 ± 1.2	5.7 ± 0.4	7.1 ± 0.3	6.4 ± 0.5
	4	34.8 ± 1.6	6.4 ± 0.2	15.6 ± 0.6	7.3 ± 0.2
	6	30.5 ± 1.4	4.3 ± 0.1	6.5 ± 0.2	5.2 ± 0.3
	24	18.4 ± 1.5	Nil	2.1 ± 0.5	4.6 ± 0.6
Coupled SLNs	2	33.7 ± 1.2	4.5 ± 0.4	39.3 ± 0.5	7.1 ± 0.1
	4	35.5 ± 1.3	5.2 ± 0.6	47.7 ± 0.4	7.6 ± 0.3
	6	31.6 ± 0.8	3.4 ± 0.3	42.1 ± 0.4	5.2 ± 0.6
	24	22.4 ± 1.5	Nil	35.3 ± 0.2	2.5 ± 0.2

SD ±  mean (n = 3)