Table 2.
Analysis of variance of responses
| Source | SS | DF | MS | F value | p value | |
|---|---|---|---|---|---|---|
| Model | 9,493.77 | 4 | 2,373.44 | 144.36 | <0.0001 | Significant |
| A (polymer concentration) | 8,665.86 | 1 | 8,665.86 | 527.10 | <0.0001 | |
| B (CaCl2 concentration) | 672.71 | 1 | 672.71 | 40.92 | <0.0001 | |
| A2 | 72.27 | 1 | 72.27 | 4.40 | 0.0477 | |
| B2 | 82.93 | 1 | 82.93 | 5.04 | 0.0351 | |
| Residual | 361.69 | 22 | 16.44 | |||
| Lack of fit | 43.67 | 4 | 10.92 | 0.62 | 0.6554 | Not significant |
| Pure error | 318.02 | 18 | 17.67 | |||
| Total | 9,855.46 | 26 |
This analysis of responses is in terms of total drug that remained in the beads (before exposure to the simulated colonic tract fluid) SS, sum of squares; DF, degree of freedom; MS, mean square; F value, factor effect value; p value, probability value.