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Comparison of the distributions of 131I-P-GUS and 131I-NP-GUS in various tissues 10 min after i.v. injection in 2-day-old mice. 131I-P-GUS or 131I-NP-GUS (550,000 cpm of each) was injected. The distribution volumes of the brain (A), heart (B), lung (C), liver (D), spleen (E), and kidney (F) were normalized by the percent of 131I-P-GUS in each tissue. n = 4-5 mice per mean. Asterisks indicate a significant difference from the control value: *, P < 0.05; **, P < 0.01; ***, P < 0.001.
